What are the Benefits of Metastatic Breast Cancer Research Study?

One in every eight women in the United States is expected to receive a breast cancer diagnosis at some point in her life. The prevalence of breast cancer among women is alarming, especially if the disease reaches its final stages. Stage IV or Metastatic breast cancer has adverse effects on overall health, quality of life, and life expectancy. However, with the potential of a metastatic breast cancer research study, there are chances of improvement.

Studies have shown that clinical trials have increased the possibility of survival in cancer patients, thanks to advanced treatments and early diagnosis.  

Introduction to Metastatic Breast Cancer  

Breast cancer refers to the uncontrolled and abnormal multiplication of cells in the breast. These cells combine to form tumors in the ducts and lobules of the breasts. Generally, this growth is not fatal during the initial stages, but when left unattended, it can spread to other organs. This spreading of breast cancer cells in different parts of the body is called metastasis and leads to stage IV or metastatic breast cancer. Around 30% of women diagnosed with early-stage breast cancer are likely to experience the development of metastases. 

Signs and symptoms  

Symptoms of early breast cancer vary based on where and how it grows. Some common signs include the development of a lump in breasts or armpits, changes in breast appearance, chronic fatigue, loss of appetite, and weight loss. As the cancer progresses in the body, the symptoms expand according to the target organ. These are a few possible symptoms people experience when breast cancer metastasizes to other organs: 

Metastasis to bones 

Metastasis to liver  

Metastasis to brain 

Metastasis to lungs 

Diagnosis of Metastatic Breast Cancer  

Just as the symptoms of metastatic breast cancer differ according to the organ it targets, so does the diagnosis. For example, if the doctors suspect it has progressed to the brain, they may advise a brain MRI. Similarly, if someone has symptoms that indicate liver metastasis, they may be asked for blood tests like CBC and LFT. Other times, a biopsy, Fibro Scan, ultrasound, or PET scan would be recommended. For cases of lung metastasis, medical professionals may recommend a bronchoscopy or a mucus examination.  

Current treatments for Metastatic Breast Cancer 

Endocrine therapy: Hormone receptor (HR)-positive metastatic breast cancer is treated with these therapies to assist in reducing or slowing the progression of the disease. This type of therapy targets cells that are sensitive to hormones like estrogen.  

• Chemotherapy: This is either used in collaboration with other drugs or on its own to target and kill cancer-causing cells in the body.  

• FDA-approved targeted therapies: These involve antibodies that intensify the power of a patient’s immune system to recognize and attack cancer cells. They also help recognize targets and receptors on harmful cells. Moreover, some options suppress the functions of enzymes involved in DNA repair, i.e., the PARP inhibitors and CDK4/6-inhibitors.  

• Local therapy: Examples of this method involve utilizing surgery and radiation targeted at particular areas where breast cancer has disseminated. Although they might be used to ease pain and symptoms associated with the target organ, they do not eliminate the cancer.  

Clinical Trials for Metastatic Breast Cancer: Functions and Benefits 

Clinical trials play an important role in discovering new and improved methods of treating diseases. Their foundation rests on scientific research and technological advancements, striving to provide the best means of medical care to patients. They pave the way for early diagnosis, careful follow-ups, and a patient-centric approach.  

Role of Cancer Clinical Trials 

Research in clinical trials studies every aspect of metastasis to ensure a proper understanding of how the disease progresses. Cancer clinical trials cover the following details: 

Benefits of cancer research in clinical trials 

Access to best treatments 

The dangers associated with cancer are not as critical today as they were five years ago. This has only been possible as a result of the elaborate and careful research that takes place in a cancer clinical trial. By participating in a clinical trial, cancer patients can access the most advanced and beneficial treatments before they even become accessible to other people.  

Early diagnosis and close monitoring 

Participants in clinical trials generally receive more attentive monitoring from their healthcare providers compared to other patients. The research protocol usually requires a specific number of imaging tests and face-to-face consultations. Additionally, you will have access to an extended team of physicians and nurses who are available to respond to inquiries and alleviate any concerns you may have. Not only is this reassuring but also a benchmark for early diagnosis and preventive care.  

Contribution to the Cancer Society and medical advancement 

Trials that took place in the past are now the reason for today’s innovative cancer therapies. Patients who participate in cancer clinical trials help develop a futuristic medical approach that benefits other cancer patients.  

Preventing Breast Cancer 

According to the Centers for Disease Control and Prevention (CDC), these are some measures one can take to lower the risk of breast cancer: 

Conclusion: The Effectiveness of Metastatic Breast Cancer Research 

The incidence of breast cancer in women is concerning, given that a great number of cases proceed to stage IV. Metastatic breast cancer can take a toll on physical and emotional health, determining how long someone might live. But there’s hope with ongoing research in this area.  

Clinical trials have been shown to boost survival rates for cancer patients. This is due to the advancement in treatment methodologies and timely disease identification. People with cancer should not miss out on the benefits of a clinical trial. Hence, if you are someone who has been diagnosed with cancer, consider enrolling in the highest-paid clinical trials near you.