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In summary, ribosomes are the unsung heroes in the storyline of cardiac hypertrophy development and progression. Taking aim at the ribosomes and the pathways they influence could open the door to innovative treatments for this heart condition and its related complications. Nonetheless, we're still a few puzzle pieces short of comprehending fully the intricate mechanisms orchestrated by ribosomes in facilitating cardiac hypertrophy and pinpointing precise targets for a therapeutic approach.